| | 57470004 | 10/9/2021 | 5:00 PM | St. / St. Ambrose Gym - VBCourt 1 | St. Christopher (Rudy) | 60 | St. Francis Xavier (Alessio) | 50 |
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| | 57470003 | 10/9/2021 | 6:00 PM | Elyr / Elyria Catholic HS Gym | St. Joseph - Avon Lake (Henry) | 51 | Holy Trinity - Avon (Shim) | 42 |
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| | 57470001 | 10/10/2021 | 1:00 PM | Elyr / Elyria Catholic HS Gym | St. Mary of the Falls (Maly) | 20 | St. Ambrose (O'Donnell) | 50 |
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| | 57470002 | 10/10/2021 | 1:00 PM | Seton Catholic School-Hudson / Seton Catholic-Gym | Holy Family - Stow (Waite) | 50 | St. Hilary (Johnson) | 40 |
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| | 57470006 | 10/10/2021 | 1:00 PM | St. Rita-Solon / St. Rita Gym | Mater Dei Catholic Academy (McLaughlin) | 46 | Seton Catholic School (Santoro) | 51 |
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| | 57470005 | 10/10/2021 | 2:00 PM | Elyr / Elyria Catholic HS Gym | Our Lady of Angels (Ruane) | 55 | St. Charles Borromeo (McCarthy) | 56 |
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| | 57470008 | 10/16/2021 | 10:30 AM | St. Jude-Elyria / St. Jude - Gym | Our Lady of Angels (Ruane) | 27 | Sts. Joseph and John (Cantwell) | 50 |
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| | 57470009 | 10/16/2021 | 11:30 AM | St. Jude-Elyria / St. Jude - Gym | St. Christopher (Rudy) | 22 | St. Ambrose (O'Donnell) | 50 |
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| | 57470010 | 10/16/2021 | 3:00 PM | St. Michael-Independence / St. Michael-Rappe Hall | St. Joseph - Avon Lake (Henry) | 26 | Holy Family - Stow (Waite) | 50 |
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| | 57470007 | 10/16/2021 | 3:30 PM | Seton Catholic School-Hudson / Seton Catholic-Gym | Seton Catholic School (Santoro) | 25 | St. Albert the Great (Coundourides) | 50 |
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| | 57470011 | 10/17/2021 | 3:30 PM | St. Michael-Independence / St. Michael-Rappe Hall | Holy Family - Stow (Waite) | 31 | St. Albert the Great (Coundourides) | 50 |
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| | 57470012 | 10/17/2021 | 5:00 PM | Luth / Lutheran West-Rock Gym | St. Ambrose (O'Donnell) | 60 | Sts. Joseph and John (Cantwell) | 65 |
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| | 57470013 | 10/24/2021 | 2:30 PM | Ursuline College-Pepper Pike / Siedman Gymnasium | Sts. Joseph and John (Cantwell) | 47 | St. Albert the Great (Coundourides) | 52 |
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